Protein Details: Glycine receptor subunit alpha-1

Protein ID

ICDB_Pro_0306

Protein Name

Glycine receptor subunit alpha-1

Gene Name

Glra1; Glyr

Organism

Rattus norvegicus (Rat)

Length

457 amino acids

AlphaFoldDB

AF-P07727-F1-model_v4.pdb

Function

Sequence

MYSFNTLRFYLWETIVFFSLAASKEADAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKSPMLNLFQDDEGGEGRFNFSAYGMGPACLQAKDGISVKGANNNNTTNPAPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIVRREDVHNK

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

220;222;230-235;243;289

Disease

Location

Detected in spinal cord (at protein level). Detected in spinal cord and brain stem.